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Methods for the behavioural phenotyping of mouse mutants. How to keep the overview
1University of Cologne, Anatomy II, Cognitive Neurobiology, Joseph-Stelzmann-Str. 9, 50931 Cologne, Germany. mmb-network@medizin.uni-koeln.de
Behavioural Brain Research
|October 30, 2001
Summary
The Mutant Mice Behaviour-network (MMB) is a new international forum for discussing genetically engineered mouse behavior. It aims to create a standardized database for reproducible behavioral phenotyping and interdisciplinary consensus.
Area of Science:
- Neuroscience
- Genetics
- Animal Behavior
Background:
- Genetically engineered mice are crucial for modeling human diseases.
- Standardized behavioral phenotyping is essential for reproducible research.
Purpose of the Study:
- To establish the Mutant Mice Behaviour-network (MMB) as an international forum.
- To create a standardized, internet-based database for genetically engineered mouse behavior.
- To promote reproducible behavioral phenotyping methods.
Main Methods:
- Founding a non-profit, international forum (MMB).
- Developing an internet-based, standardized database.
- Documenting parameters affecting mouse behavior.
Main Results:
- Establishment of the MMB network.
- Initiation of a standardized database for behavioral phenotyping parameters.
- Foundation for reproducible mouse behavioral testing.
Conclusions:
- The MMB network will facilitate discussion and standardization of behavioral phenotyping.
- A standardized database is key to achieving comprehensible and reproducible tests.
- The initiative aims to foster interdisciplinary consensus on mouse behavioral phenotyping methods.