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Retrometabolic drug design--novel aspects, future directions
1IVAX Corporation, Miami, Florida, USA. Nicholas_Bodor@ivax.com
Die Pharmazie
|November 1, 2001
Abstract:
A brief overview of the general, retrometabolic drug design principles, including soft drug and chemical delivery system design, is presented. Selected recent developments within these fields are also summarized, including results related to the design of soft bufuralol and amiodarone analogues, to the airway activity of loteprednol etabonate, a soft corticosteroid, and to the brain targeted delivery of some neuropeptides.