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Improved Rodent Model of Myocardial Ischemia and Reperfusion Injury
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Selenium content and blood antioxidant activity in rats with hereditary arterial hypertension during experimental
G S Yakobson1, A R Antonov, A V Golovatyuk
1Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Bulletin of Experimental Biology and Medicine
|November 1, 2001
Abstract:
The dynamics of selenium content in the plasma, lymph, and myocardium and plasma antioxidant activity were studied in male NISAG (hereditary stress-induced arterial hypertension) and Wistar rats with acute myocardial infarction and during recovery. In NISAG rats the decrease in selenium content correlated with the decrease in antioxidant activity. This probably aggravates the symptoms of experimental myocardial infarction in animals with hereditary arterial hypertension.
