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Matching reference materials with AOAC International methods of analysis.

W R Wolf1, J DeVries, W Ikins

  • 1US Department of Agriculture, Beltsville, MD, USA. wolf@bhnrc.usda.gov

Fresenius' Journal of Analytical Chemistry
|November 2, 2001
PubMed
Summary
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Ensuring equivalent analytical performance across labs requires validated methods and appropriate reference materials (RM). AOAC International is launching a peer-reviewed program to formally recognize specific RM matches for AOAC methods, enhancing reliability.

Area of Science:

  • Analytical Chemistry
  • Laboratory Science
  • Method Validation

Background:

  • Validated analytical methodology and appropriate reference materials (RM) are crucial for ensuring equivalent analytical performance in diverse laboratories.
  • Selecting RMs that match the analyte, matrix, and method applicability is key for reliable results.

Purpose of the Study:

  • To establish a formal program for recognizing the matching of specific reference materials (RM) to specific AOAC methods of analysis.
  • To address requests for a standardized system for RM/method matching (RM/MM).

Main Methods:

  • Implementation of a peer-reviewed selection system overseen by the AOAC Official Methods Board and the Technical Division on Reference Materials (TDRM) executive committee.
  • Submission of potential RM/MM proposals to an RM/MM committee for technical review.

Related Experiment Videos

  • Recommendation of acceptable matches for review through the existing AOAC process for new and modified methods.

    • Main Results:

    • Development and testing of the RM/MM recognition system using several trial matches.
    • Establishment of a structured process for validating RM suitability for specific AOAC methods.

    Conclusions:

    • The AOAC International Technical Division on Reference Materials (TDRM) is implementing a new program to formally recognize specific reference material (RM) and method matches.
    • This initiative will enhance analytical method performance equivalence and provide a reliable resource for laboratories, available via document or online.