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Immunophenotypic profile and FISH analysis in a case of Ewing's sarcoma
N Papadopoulos1, D Tamiolakis, M Lambropoulou
1Department of Pathology, Democritus University of Thrace, Dragana, 68 100 Alexandroupolis, Greece.
In Vivo (Athens, Greece)
|November 7, 2001
Abstract:
Ewing's sarcoma arising in the right fibula was diagnosed in a 12 years old female, considering clinical presentation, radiological findings and histological features. Our work points towards a possible neuroectodermal origin of Ewing's sarcoma, since MIC2/12E7 marker was found to be positive. Translocation t (11;22) (q24;q12) was found as the main cytogenetic change in this tumor, by means of FISH analysis.