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Updated: Aug 5, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Imaging for the snoring and sleep apnea patient
1Pulmonary, Allergy and Critical Care Division, Department of Medicine, Center for Sleep and Respiratory Neurobiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA. rschwab@mail.med.upenn.edu
Upper airway imaging reveals how obstructive sleep apnea develops and how treatments work. These techniques are crucial for understanding airway anatomy and guiding surgical or oral appliance therapies for sleep apnea.
Area of Science:
- Medical Imaging
- Sleep Medicine
- Otolaryngology
Background:
- Obstructive sleep apnea (OSA) pathogenesis and treatment mechanisms are increasingly understood through advanced upper airway imaging.
- Static and dynamic imaging studies analyze upper airway structure and function during wakefulness and sleep.
Purpose of the Study:
- To review the role of upper airway imaging in understanding OSA.
- To highlight the importance of imaging in evaluating therapeutic interventions.
Main Methods:
- Review of static and dynamic imaging studies.
- Examination of upper airway anatomy and function during wakefulness and sleep.
- Analysis of imaging findings related to weight loss, mandibular repositioning devices, and surgery.
Main Results:
- Imaging emphasizes the role of lateral pharyngeal walls, tongue, and soft palate in airway caliber modulation.
- Upper airway imaging elucidates anatomical changes associated with weight loss, oral appliances, and surgery.
- MR imaging, nasopharyngoscopy, and cephalometrics are key imaging modalities for specific OSA interventions.
Conclusions:
- Upper airway imaging is essential for patients undergoing upper airway surgery (e.g., UPPP) and potentially for oral appliance evaluation.
- Imaging provides a framework for understanding airway closure in OSA, potentially leading to improved treatments.
- Further investigations using imaging may yield more effective therapeutic options for sleep apnea patients.
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