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Dendritic cell subsets and costimulation for effector T-cell responses
1MRC Centre for Immune Regulation, Department of Immunology and Infection, The Medical School, University of Birmingham, UK. p.j.l.lane@bham.ac.uk
Current Opinion in Pharmacology
|November 17, 2001
Abstract:
The past year has seen major advances in the understanding of dendritic cell biology and of the costimulatory molecules that dendritic cells use to prime effector T cells and memory T cells. Recent work has revealed the specialization between different dendritic cell subsets and how this relates to their different functions in optimizing T-cell help for antibody responses and inflammatory T-cell responses.