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Updated: Oct 3, 2026

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
Published on: August 1, 2018
[MR-angiography in portal hypertension. State of the art]
R Vosshenrich1, U Fischer, E Grabbe
1Abt. Röntgendiagnostik I, Klinikum der Georg-August-Universität, Robert-Koch-Strasse 40, 37075 Göttingen. roe1@med.uni-goettingen.de
Abstract:
When imaging the portal vascular system colour-coded sonography and CT angiography are used as an alternative to intraarterial DSA. Today fast CE 3D-MRA is the imaging modality of choice in the diagnostic of patients with portal hypertension. It enables a clear picture of the portalvenous vascular system and portalsytemic shunts. Statements regarding velocity and direction of blood flow can be made with additional use of TOF and PC techniques. CE-3D MRA can be used preoperatively before liver transplantation or shunt surgery. In the follow-up of interventional or surgical procedures exact statements concerning haemodynamically significant pathologies e.g. vascular thromboses, stenoses and occlusions can be made. Patient consent is symplify and the numbers of complications can be reduced as well as duration of surgery minimized applying this technique.
Insights
Contrast-enhanced 3D MR angiography (CE-3D MRA) is the preferred imaging method for diagnosing portal hypertension. This technique offers clear visualization of the portal venous system and shunts, aiding surgical planning and follow-up.
Area of Science:
- Radiology and Medical Imaging
- Vascular Imaging
- Hepatology
Context:
- Portal hypertension diagnosis often involves non-invasive imaging alternatives like colour-coded sonography and CT angiography.
- Fast CE 3D-MRA has emerged as the leading imaging modality for patients with portal hypertension.
Purpose:
- To evaluate the utility of CE-3D MRA in diagnosing and managing portal hypertension.
- To assess the role of TOF and PC techniques in conjunction with CE-3D MRA for blood flow analysis.
Summary:
- CE-3D MRA provides clear visualization of the portal venous system and portosystemic shunts.
- Additional use of Time-of-Flight (TOF) and Phase Contrast (PC) techniques allows for assessment of blood flow velocity and direction.
- This modality is valuable for preoperative planning (liver transplantation, shunt surgery) and postoperative follow-up of interventions.
Impact:
- CE-3D MRA simplifies patient consent and can reduce complications and surgery duration.
- It enables precise evaluation of hemodynamically significant pathologies such as vascular thromboses, stenoses, and occlusions.
- Facilitates improved patient management and outcomes in portal hypertension cases.
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