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Cherubism: case reports and literature review
C L Pulse1, M S Moses, D Greenman
1Columbia University School of Dental and Oral Surgery, New York, NY, USA.
Dentistry Today
|November 22, 2001
Summary
Two mild cherubism cases presented with mandibular lesions. Diagnosis stemmed from unerupted molars, highlighting the disease
Area of Science:
- Dentistry
- Genetics
- Oral Pathology
Background:
- Cherubism is a rare genetic disorder affecting the jawbones.
- It typically manifests in childhood, causing characteristic facial swelling and bone lesions.
Observation:
- Two new cases of cherubism (Grade I severity) were documented.
- Both cases presented with bilateral, posterior mandibular lesions.
- Lesions appeared as multiloculated, radiolucent areas on imaging.
Findings:
- Diagnosis was prompted by unerupted mandibular molars (tooth #19).
- Clinical presentation varied, aligning with a wide spectrum of cherubism.
- Literature review confirmed diverse clinical expressions and treatment approaches.
Implications:
- Early detection of unerupted teeth can aid cherubism diagnosis.
- Understanding the disease spectrum is crucial for appropriate management.
- Further research may refine treatment strategies for cherubism.