Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alstrom syndrome: a case report.

F Koray1, C Dorter, Y Benderli

  • 1Department of Conservative Dentistry, Faculty of Dentistry, University of Istanbul, Capa, Turkey. dorter@superonline.com

Journal of Oral Science
|December 6, 2001
PubMed
Summary

Alstrom syndrome (AS) patients may exhibit unique oral health issues, including gingivitis and discolored enamel bands on anterior teeth. Histological analysis revealed abnormalities in the gingiva, offering new insights into AS manifestations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of weight intervention-induced changes in pathological fat mass of patients with extreme obesity and anorexia nervosa on adipokines and visceral adipocyte functions: a prospective, comparative, observational study.

European review for medical and pharmacological sciences·2024
Same author

Signature of spin-phonon coupling driven charge density wave in a kagome magnet.

Nature communications·2023
Same author

Zinc affects nuclear factor kappa b and DNA methyltransferase activity in C3H cancer fibroblast cells induced by a 2100 MHz electromagnetic field.

Electromagnetic biology and medicine·2022
Same author

No association of anti-osteoporosis drugs with COVID-19-related outcomes in women: a nationwide cohort study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2021
Same author

Gap-like feature observed in the non-magnetic topological insulators.

Journal of physics. Condensed matter : an Institute of Physics journal·2019
Same author

Influence of Different Restoration Techniques on Fracture Resistance of Root-filled Teeth: In Vitro Investigation.

Operative dentistry·2017

Area of Science:

  • Dentistry
  • Genetics
  • Oral Pathology

Background:

  • Alstrom syndrome (AS) is a rare genetic disorder with multisystemic effects including obesity, vision loss, diabetes, and hearing loss.
  • Previous research has not detailed the oral manifestations associated with Alstrom syndrome.
  • This study investigates the oral findings in two patients diagnosed with Alstrom syndrome.

Observation:

  • Both Alstrom syndrome cases presented with gingivitis.
  • Light yellow-brown discolored enamel bands were observed on the anterior teeth of both patients.
  • The observed enamel discoloration may be linked to underlying, subtle band-like enamel hypoplasia.

Findings:

  • Histological examination of gingival tissue revealed irregular basal lamina thickness.

Related Experiment Videos

  • Transmission electron microscopy identified delamination of the myelin sheath in the gingiva.
  • These findings represent the first report of pathological odontogenesis and gingival histological changes in Alstrom syndrome.

    • Implications:

    • The oral findings in this study expand the known clinical spectrum of Alstrom syndrome.
    • Understanding these oral manifestations can aid in comprehensive patient management.
    • This research highlights the need for further investigation into the oral and dental aspects of Alstrom syndrome.