Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Environment-sensitive hydrogels for drug delivery.

Y Qiu1, K Park

  • 1Departments of Pharmaceutics and Biomedical Engineering, Purdue University, West Lafayette, IN 47907-1336, USA.

Advanced Drug Delivery Reviews
|December 18, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A single institutional experience of thymic epithelial tumours over 11 years: clinical features and outcome and implications for future management.

British journal of cancer·2007
Same author

Influence of OATP1B1 genotype on the pharmacokinetics of rosuvastatin in Koreans.

Clinical pharmacology and therapeutics·2007
Same author

Significant association between leukoaraiosis and metabolic syndrome in healthy subjects.

Neurology·2007
Same author

A large foot ulcer due to disseminated Mycobacterium avium infection in a patient with previously undiagnosed HIV infection.

The British journal of dermatology·2007
Same author

New clinical grading system for chronic GVHD predicts duration of systemic immunosuppressive treatment and GVHD-specific and overall survival.

Bone marrow transplantation·2007
Same author

EGFR gene and protein expression in breast cancers.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2007
Same journal

Silicone oil in protein drug products and its implications for formulation stability.

Advanced drug delivery reviews·2026
Same journal

Targeted delivery of proteolysis-targeting chimeras (PROTAC) and molecular glue degraders (MGD).

Advanced drug delivery reviews·2026
Same journal

Lysosome-targeting degrader delivery system: from formulation design to biomedical applications.

Advanced drug delivery reviews·2026
Same journal

Anti-PEG antibodies in nanomedicine: Mechanisms, risks, and opportunities.

Advanced drug delivery reviews·2026
Same journal

Optimizing macrophage-targeted intracellular delivery systems for safe and effective immunotherapies.

Advanced drug delivery reviews·2026
Same journal

Light-controlled CRISPR-dCas9 epigenome editing: advanced drug-delivery strategies and oncology applications.

Advanced drug delivery reviews·2026
See all related articles

Environmentally sensitive hydrogels offer promise for targeted drug delivery, but current systems are too slow and fragile. Future research aims to develop faster, stronger, and biocompatible hydrogels for advanced applications.

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Drug Delivery Systems

Background:

  • Environmentally sensitive hydrogels respond to stimuli like pH, temperature, and molecules.
  • These hydrogels are explored for site-specific drug delivery, biosensing, and bioseparation.
  • Current hydrogel applications are limited by slow response times and poor mechanical strength.

Purpose of the Study:

  • To review the potential of environmentally sensitive hydrogels in various applications.
  • To identify key challenges hindering practical applications of these hydrogels.
  • To highlight areas for future development in hydrogel technology.

Main Methods:

  • Literature review of stimuli-responsive hydrogel research.
  • Analysis of hydrogel properties, including response time, mechanical strength, and biocompatibility.

Related Experiment Videos

  • Discussion of synthesis strategies for improved hydrogel performance.

    • Main Results:

    • Environmentally sensitive hydrogels show promise for controlled drug delivery and biosensing.
    • Key limitations include slow response times and insufficient mechanical integrity.
    • Biocompatibility and biodegradability are critical factors for in vivo applications.

    Conclusions:

    • Significant improvements in hydrogel properties are needed for widespread adoption.
    • Developing faster-acting, mechanically robust, and biocompatible hydrogels is essential.
    • Future advancements in polymer synthesis hold the key to realizing the full potential of responsive hydrogels.