Related Experiment Video
Updated: Aug 18, 2026

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
Published on: January 31, 2018
Why is DNA damage signaling so complicated? Chaos and molecular signaling
1AGI Dermatics, Freeport, New York 11520, USA. danyarosh@agiderm.com
Abstract:
Molecular signaling in eukaryotic cells is accomplished by complex and redundant pathways converging on key molecules that are allosterically controlled by a limited number of signaling proteins. The p53-signaling pathway is an example of a complicated sequence of signals produced in response to DNA damage. This pattern of signaling may arise from chance occurrences at the origin of life and the necessities imposed on a nanomolar system. From this viewpoint, chaos theory may explain the origin, complexity, and convergence of these pathways.
Related Concept Videos
Overview of DNA Repair
Chemically...
Fixing Double-strand Breaks
DNA Damage can Stall the Cell Cycle
Overview of DNA Repair
Chemically...
Fixing Double-strand Breaks
DNA Damage Can Stall the Cell Cycle

