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Gramene: a resource for comparative grass genomics.

Doreen Ware1, Pankaj Jaiswal, Junjian Ni

  • 1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

Nucleic Acids Research
|December 26, 2001
PubMed
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Gramene is a new database for grass genomes, serving as a vital resource for rice research. It integrates genetic and sequence data, facilitating comparative genomics across grass species.

Area of Science:

  • Comparative genomics
  • Bioinformatics
  • Plant science

Background:

  • Rice is a model monocot for understanding grass genomes.
  • Existing databases like RiceGenes lack comprehensive integration.
  • There is a need for a unified resource for grass comparative genomics.

Purpose of the Study:

  • To introduce Gramene, a new comparative genome mapping database for grasses.
  • To provide an integrated platform for rice genomic information.
  • To facilitate comparative studies across different grass species.

Main Methods:

  • Developed a relational database using Oracle.
  • Integrated curated data on maps, sequences, genes, markers, mutants, and QTLs.
  • Established Gramene as a central portal for grass genomic resources.

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Main Results:

  • Gramene offers curated and integrative information for rice.
  • The database uses rice genetic, physical, and sequence maps as organizing units.
  • Gramene serves as a portal to interconnect with other web-based grass resources.

Conclusions:

  • Gramene is a significant advancement in grass comparative genomics.
  • The database provides a common framework for cross-species grass research.
  • Gramene enhances accessibility and integration of genomic data for the scientific community.