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Arterial port catheter system placement using a translumbar aortic route
Timothy W I Clark1, John M Bilo, J Robert Beecroft
1Department of Radiology, Dalhousie University, Halifax, Canada. clark@oasis.rad.upenn.edu
Investigative Radiology
|December 26, 2001
Summary
Translumbar aortic placement of arterial infusion ports is feasible in swine. Overcoming catheter dislodgement is key for this potential new access site in regional chemotherapy and gene therapy.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Medical Device Technology
Background:
- Implantable ports for arterial infusion are increasingly used for regional chemotherapy and gene therapy.
- Percutaneous arterial port placement faces anatomical challenges at existing access sites.
- The translumbar aortic approach offers a potential alternative for long-term arterial access.
Purpose of the Study:
- To assess the feasibility of translumbar aortic placement of a port-catheter system for long-term arterial infusion.
- To evaluate the patency and position of the translumbar aortic port-catheter system in a swine model.
Main Methods:
- Eight swine underwent percutaneous placement of an arterial port-catheter system via a translumbar aortic approach.
- Catheter tips were positioned in the hepatic arteries, with ports in the paraspinal subcutaneous tissues.
- Tissue adhesive was used in two animals to improve catheter fixation.
Main Results:
- Immediate technical success was achieved in 75% (6/8) of animals.
- Catheter dislodgement occurred in several animals, with varying degrees of success in fixation.
- Three port-catheter systems remained functional with correct hepatic artery positioning at 28 days.
Conclusions:
- Percutaneous translumbar aortic port-catheter system placement is feasible in swine.
- Catheter fixation remains a significant challenge for clinical application.
- This approach holds potential as an ancillary access site if fixation issues are resolved.