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Invasive Salmonella virchow infection in childhood
M Bitsori1, E Galanakis, S Maraki
1Department of Paediatrics, University of Crete, Heraklion, Greece.
Scandinavian Journal of Infectious Diseases
|January 5, 2002
Summary
Salmonella virchow can cause invasive infections like bacteremia and abscesses in healthy children, challenging previous assumptions about its lower invasiveness. Prompt antibiotic treatment is crucial for recovery.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Salmonella virchow is typically classified as a less invasive non-typhoidal Salmonella serotype.
- Previous reports have indicated sporadic invasive cases, but its potential for broader invasive disease in children was not well-established.
Observation:
- Three otherwise healthy children presented with Salmonella virchow bacteremia.
- These cases were complicated by monoarthritis and prevertebral abscess, with only one child having a history of gastroenteritis.
Findings:
- The study details successful treatment of these invasive Salmonella virchow infections using various antibiotic regimens, including cefotaxime, ceftriaxone, and clindamycin.
- All three children responded well to their respective antibiotic courses, indicating effective therapeutic options.
Implications:
- Salmonella virchow may exhibit greater invasive potential in immunocompetent children than previously recognized.
- This serotype can manifest with a wider range of clinical presentations, including severe systemic infections, necessitating increased clinical vigilance.