Related Experiment Video
Updated: Aug 8, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Hypersensitivity to warfarin in a patient with a mechanical aortic prosthesis
1Department of Medicine, Scott & White Memorial Hospital and Clinic, Scott, Sherwood and Brindley Foundation, The Texas A&M University System Health Science Center College of Medicine, Temple 54449, USA.
Abstract:
The case of a patient with a prosthetic aortic valve and warfarin hypersensitivity is presented. On rechallenging the patient with warfarin, a spongiotic dermatitis with heavy superficial perivascular lymphocytic infiltrates with eosinophils was seen. The patient was finally discharged on aspirin therapy alone and is doing well to date. Warfarin hypersensitivity is rare, and only incidental reports exist regarding its incidence and management. It is conceivable that newer antiplatelet agents, whether alone or in combination with aspirin, will provide better control of thromboembolic events in patients with warfarin intolerance.
Related Concept Videos
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Aortic Regurgitation III: Medical Management
Peripheral Artery Disease V: Postoperative Nursing Management
Aneurysm III: Interprofessional Care
Aneurysm IV: Nursing Management
Venous Thrombosis III: Interprofessional Care

