Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

History of Microbiology01:28

History of Microbiology

16.1K
Microbiology, a scientific field dedicated to the study of microorganisms, has undergone profound development since its inception in the 17th century. Its history is marked by key discoveries and technological advancements that have shaped our understanding of life at the microscopic level and transformed medicine, agriculture, and industry.Early Foundations of MicrobiologyThe early foundations of microbiology were built on groundbreaking observations and the development of pioneering...
16.1K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1.4K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.4K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

837
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
837
Key Techniques in Microbiology01:19

Key Techniques in Microbiology

3.0K
Aseptic techniques prevent contamination, ensure experimental accuracy, and protect researchers and microbial cultures. These techniques are essential in clinical, industrial, and research settings where sterility is required.Maintaining Sterility in Laboratory PracticesScientists maintain sterility by sterilizing tools with heat or chemicals, disinfecting work surfaces, and handling cultures in controlled environments. Working near an open flame or within a laminar flow hood reduces the risk...
3.0K
Introduction to Microbial Ecology01:28

Introduction to Microbial Ecology

54
Microbial ecology examines the complex web of interactions and diversity among microorganisms within various ecosystems. This field seeks to understand how microbial populations adapt to and influence their environments and how these interactions shape broader ecological processes. Microbes are integral to ecosystem function, participating in nutrient cycling, energy flow, and the maintenance of environmental homeostasis.An ecosystem represents a dynamic interaction between living organisms...
54
Introduction to the Human Microbiota01:22

Introduction to the Human Microbiota

76
Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity,...
76

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

2',7'-bis-(Carboxyethyl)-5-(6')-Caroboxyfluorescein (BCECF) as a probe for intracellular fluorescence polarization measurements.

Journal of biomedical optics·2012
Same author

Laser beam shaping and spot size.

Current protocols in cytometry·2008
Same author

Falling estradiol levels as a result of intentional reduction in gonadotrophin dose are not associated with poor IVF outcomes, whereas spontaneously falling estradiol levels result in low clinical pregnancy rates.

Human reproduction (Oxford, England)·2004
Same author

Violet laser diodes as light sources for cytometry.

Cytometry·2001
Same author

Multiparameter flow cytometry of bacteria: implications for diagnostics and therapeutics.

Cytometry·2001
Same author

Optical measurements in cytometry: light scattering, extinction, absorption, and fluorescence.

Methods in cell biology·2000
Same journal

Advances in Hemostasis Laboratory Testing.

Clinics in laboratory medicine·2026
Same journal

Extracellular Vesicles in Hemostasis.

Clinics in laboratory medicine·2026
Same journal

Thrombin Generation Assay: Ready for Prime Time.

Clinics in laboratory medicine·2026
Same journal

Viscoelastic Testing for the Laboratorian: Recent Advances and Practical Advice.

Clinics in laboratory medicine·2026
Same journal

Practical Recommendations for Harmonization of Hemostasis Testing Across Hospital Sites.

Clinics in laboratory medicine·2026
Same journal

The Role of Hypoxia in Vascular Endothelial Dysfunction and Venous Thromboembolism.

Clinics in laboratory medicine·2026
See all related articles

Related Experiment Video

Updated: Apr 2, 2026

Biology of Microbial Communities - Interview
14:42

Biology of Microbial Communities - Interview

Published on: May 28, 2007

9.2K

Microbiology.

H M Shapiro1

  • 1hms@shapirolab.com

Clinics in Laboratory Medicine
|January 5, 2002
PubMed
Summary
This summary is machine-generated.

Flow cytometry offers rapid microorganism detection but is not cost-effective. New fluorescence multiplexing and microfluidic technologies may soon enable affordable cytometric tools for clinical microbiology labs.

More Related Videos

Aseptic Laboratory Techniques: Plating Methods
18:00

Aseptic Laboratory Techniques: Plating Methods

Published on: May 11, 2012

760.3K
Single-cell Microfluidic Analysis of Bacillus subtilis
10:37

Single-cell Microfluidic Analysis of Bacillus subtilis

Published on: January 26, 2018

12.8K

Related Experiment Videos

Last Updated: Apr 2, 2026

Biology of Microbial Communities - Interview
14:42

Biology of Microbial Communities - Interview

Published on: May 28, 2007

9.2K
Aseptic Laboratory Techniques: Plating Methods
18:00

Aseptic Laboratory Techniques: Plating Methods

Published on: May 11, 2012

760.3K
Single-cell Microfluidic Analysis of Bacillus subtilis
10:37

Single-cell Microfluidic Analysis of Bacillus subtilis

Published on: January 26, 2018

12.8K

Area of Science:

  • Clinical microbiology
  • Biotechnology
  • Analytical chemistry

Background:

  • Flow cytometry is a rapid method for detecting low concentrations of microorganisms in clinical samples.
  • Current applications are limited by cost-effectiveness for widespread clinical use.

Purpose of the Study:

  • To explore the potential of adapting advanced flow cytometry techniques for cost-effective clinical microbiology.
  • To assess the feasibility of integrating new technologies into existing laboratory workflows.

Main Methods:

  • Review of recent advancements in fluorescence multiplexing for flow cytometric bead immunoassays.
  • Evaluation of hybrid cytometers incorporating microfluidic technology.
  • Analysis of cost-effectiveness models for clinical implementation.

Main Results:

  • Adaptation of fluorescence multiplexing offers enhanced sensitivity and multiplexing capabilities.
  • Microfluidic-based hybrid cytometers show promise for reduced instrument cost and complexity.
  • These technological advancements suggest a pathway toward cost-effective cytometric solutions.

Conclusions:

  • Emerging flow cytometry methodologies, including fluorescence multiplexing and microfluidics, have the potential to overcome previous cost barriers.
  • The integration of these technologies could lead to the deployment of affordable cytometric instruments in clinical microbiology laboratories in the near future.
  • This could significantly improve the speed and efficiency of microorganism detection in clinical diagnostics.