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[The relationship between sleep related breathing disorders and stroke]
1Department of Neurology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038.
Summary
Sleep-related breathing disorders (SRBD) are more common in patients with cerebrovascular diseases (CVD). SRBD may be a significant risk factor for CVD, potentially creating a detrimental cycle with stroke.
Area of Science:
- Neurology
- Sleep Medicine
- Cardiovascular Science
Context:
- Cerebrovascular diseases (CVD) represent a significant global health burden.
- Sleep-related breathing disorders (SRBD) are increasingly recognized as potential contributors to various health conditions.
- The interplay between SRBD and CVD requires further investigation to understand underlying mechanisms and clinical implications.
Purpose:
- To investigate the association between sleep-related breathing disorders (SRBD) and cerebrovascular diseases (CVD).
- To compare the prevalence and severity of SRBD in patients with CVD versus a control group.
- To explore the potential role of SRBD as a risk factor for CVD and its impact on hypertension.
Summary:
- Polysomnography revealed a significantly higher incidence of SRBD, particularly obstructive sleep apnea, in CVD patients compared to controls.
- CVD patients with SRBD exhibited more severe apnea/hypopnea and deoxygenation, alongside lower oxygen saturation levels.
- Elevated blood pressure during sleep and a higher prevalence of hypertension were observed in CVD patients with SRBD, with SRBD identified as a significant risk factor (OR=6.28).
Impact:
- SRBD may be an independent and significant risk factor for the development of cerebrovascular diseases.
- A potential vicious cycle between stroke and SRBD could negatively influence stroke outcomes.
- Findings suggest the importance of screening for and managing SRBD in patients with or at risk for CVD.