Molecular mechanisms of chaperonin GroEL-GroES function.

O Keskin1, I Bahar, D Flatow

  • 1Molecular Structure Section, Laboratory of Experimental and Computational Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

Biochemistry
|January 10, 2002
PubMed
Summary

The GroEL-GroES complex dynamics were studied using a coarse-grained model. This revealed complex motions crucial for substrate binding and conformational changes, highlighting the protein

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