Related Experiment Video
Updated: Aug 3, 2026
Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
[Mediastinal tumors and tumor-like formations in children]
Insights
This study analyzed 143 children with mediastinal tumors, finding most were malignant. Key diagnostic symptoms and the importance of chest X-rays for pediatric mediastinal masses were highlighted.
Area of Science:
- Pediatric Oncology
- Thoracic Surgery
- Diagnostic Imaging
Context:
- Mediastinal tumors in children present a diagnostic and therapeutic challenge.
- A comprehensive review of 143 pediatric cases over 25 years provides valuable insights.
- Understanding the epidemiology and clinical presentation is crucial for timely intervention.
Purpose:
- To summarize 25 years of experience in diagnosing and treating pediatric mediastinal formations.
- To identify key presenting symptoms and diagnostic methods for mediastinal tumors in children.
- To evaluate treatment outcomes and analyze diagnostic errors.
Summary:
- Out of 143 pediatric patients (10 days to 15 years), 50 (34.96%) had benign tumors and 93 (65.04%) had malignant ones.
- Important symptom groups identified include general somatic, compressive, and neurological.
- Survey radiography of thoracic organs in two projections was the principal diagnostic method.
Impact:
- This review aids in recognizing critical symptoms of pediatric mediastinal masses.
- It underscores the importance of radiographic imaging in the early diagnosis of these conditions.
- Analysis of outcomes and errors can refine future diagnostic and treatment strategies for childhood mediastinal tumors.
Abstract:
Twenty-five years experience of diagnosis and results of treatment of 143 childs aged from 10 days to 15 years with sizable mediastinal formations was summarized. Benign tumor was revealed in 50 (34.96%) childs, malignant one--in 93 (65.04%). Groups of most important symptoms were suggested: generally somatic, compressive, neurological. Principal method of diagnosis of mediastinal tumor in children--the survey roentgenography of thoracic organs in two projection. Immediate and late follow-up results of operative intervention were estimated, diagnostic mistakes were analyzed.
Related Concept Videos
02:30Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
01:23Mitral Stenosis II: Clinical features and Diagnostic Tests