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Order out of complexity--protein structures that interact with heparin
1Laboratory for Molecular Structure, National Institute for Biological Standards and Control, Hertfordshire, UK. bmulloy@nibsc.ac.uk
Current Opinion in Structural Biology
|January 12, 2002
Abstract:
Many proteins of widely differing functionality and structure are capable of binding heparin. Structural characterisations of the many types of such complexes are being reported in ever-increasing number and at improved resolution. Several crystal structures of complexes formed through the interaction of heparin-derived oligosaccharides with one or more protein partners have been described.