Search research articles

Search research articles

Related Experiment Videos

Variceal Hemorrhage.

Lisa A. Brandenburger¹, Fredric G. Regenstein

¹Section of Gastroenterology and Hepatology, Tulane University Health Sciences Center, 1415 Tulane Avenue, New Orleans, LA 70112-2600, USA. E-mail fregens@tulane.edu

Current Treatment Options in Gastroenterology

|January 17, 2002

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same journal

Esophageal Disorders in the Older Adult.

Current treatment options in gastroenterology·2025

Same journal

Endobariatrics: a Still Underutilized Weight Loss Tool.

Current treatment options in gastroenterology·2023

Same journal

Management of Post Ablative Barrett's Esophagus: a Review of Current Practices and Look at Emerging Technologies.

Current treatment options in gastroenterology·2023

Same journal

Inflammatory Bowel Disease Therapy and Venous Thromboembolism.

Current treatment options in gastroenterology·2023

Same journal

Ileal Pouch-Anal Anastomosis in the Older Adult: a Review of Postoperative Outcomes and Pouchitis Treatment.

Current treatment options in gastroenterology·2023

Same journal

Celiac Disease in the Elderly.

Current treatment options in gastroenterology·2023

See all related articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Prophylactic beta-blockers reduce bleeding and death in cirrhosis patients. Screening for esophageal varices is recommended for those with advanced liver disease or signs of portal hypertension.

Area of Science:

Hepatology
Gastroenterology
Internal Medicine

Background:

Esophageal varices in chronic liver disease pose significant bleeding risks.
Effective management strategies are crucial for reducing morbidity and mortality.

Purpose of the Study:

To outline current recommendations for the screening and management of esophageal varices in patients with chronic liver disease.
To detail prophylactic and therapeutic approaches for preventing and treating variceal bleeding.

Main Methods:

Review of current guidelines and clinical evidence for variceal screening and treatment.
Discussion of risk factors for variceal bleeding, including variceal size, wall characteristics, and liver dysfunction.
Evaluation of pharmacologic (beta-blockers, octreotide, terlipressin) and endoscopic therapies (sclerotherapy, band ligation).

Related Experiment Videos

Main Results:

Nonselective beta-blockers are effective for primary prophylaxis against variceal bleeding.
Endoscopic screening is recommended for patients with Child's B/C cirrhosis and select Child's A patients with portal hypertension.
Combined pharmacologic and endoscopic therapy is superior for acute variceal bleeding; beta-blockers may reduce rebleeding post-endoscopic treatment.
Transjugular intrahepatic portosystemic shunts or surgery are options for refractory bleeding.

Conclusions:

Early screening and appropriate management of esophageal varices are vital in chronic liver disease.
A stepwise approach involving pharmacologic therapy, endoscopic interventions, and potentially shunting is essential for optimal patient outcomes.