[Immunoelectrophoretic studies in Marek's disease]

Immunoelectrophoretic studies were carried out with the sera obtained from 10 chickens affected with acute Marek's disease. The diagnosis was confirmed clinically, morphologically, and via the embryonic test of von Bulow. The blood sera of ten normal hens served as controls. Results showed that in the sera of the diseased chickens there were changes in the protein spectrum, whereas the alfa and gamma-globulin fractions were divided into three subfractions. The exhaustion of the diseased sera with hyperimmune sera against sera of normal chickens revealed characteristic alfa2-globulins. The results obtained were confirmed with the active anaphylaxis in guinea-pigs.