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[The effect of Paeonol on erythrocyte deformability determined by micropipette aspiration technique]
Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials
|January 22, 2002
Abstract
Objective:
The effect of Paeonol (PAE) on erythorcyet(RBC) deformability was studied in order to provide experimental data for the application in clinic and the evaluation in pharmacological action.
Methods:
Micropipette Aspiration Technique was used to determine the RBC deformation length. The method of calculation was also simplified and a new apparent deformation Index(ADI) was defined.
Results:
PAE could increase the ADImin and ADImax and decrease Tmax significantly.
Conclusion:
PAE has the effect of deformational ability on RBC. Micropipette aspiration technique is a feasible method for determining the effect of traditional Chinese medicine on erythrocyte deformability.