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p16INK4A and p14ARF tumour suppressors in melanoma: lessons from the mouse

Graeme J Walker1, Nicholas K Hayward

  • 1Human Genetics Laboratory, Queensland Institute of Medical Research, Royal Brisbane Hospital, Queensland, 4029, Brisbane, Australia.

Lancet (London, England)
|January 26, 2002
PubMed
Abstract

No abstract available in PubMed .

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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

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