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Anomalies peculiar to multiple gestations.

F D Malone1, M E D'Alton

  • 1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Sloane Hospital for Women, Columbia University College of Physicians and Surgeons, New York, New York, USA. fdm9@columbia.edu

Clinics in Perinatology
|January 31, 2002
PubMed
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Twin pregnancies have double the risk of congenital anomalies compared to singletons. This review details unique twinning-related conditions like twin-twin transfusion syndrome and conjoined twins.

Area of Science:

  • Perinatology
  • Maternal-Fetal Medicine
  • Developmental Biology

Background:

  • Congenital anomalies are more frequent in twin pregnancies than singleton pregnancies.
  • Multiple gestations face risks for structural malformations and unique conditions tied to the twinning process.

Purpose of the Study:

  • To review and describe anomalies unique to twin pregnancies.
  • To provide detailed information on twin-specific congenital conditions.

Main Methods:

  • Literature review of congenital anomalies in twin pregnancies.
  • Detailed description of twin-specific malformations.

Main Results:

  • Twin pregnancies exhibit a higher incidence of congenital anomalies.

Related Experiment Videos

  • Unique conditions in twins include twin-twin transfusion syndrome, twin-reversed-arterial-perfusion syndrome, and conjoined twinning.

    • Conclusions:

    • Twin pregnancies are at increased risk for a spectrum of congenital anomalies.
    • Understanding twin-specific anomalies is crucial for diagnosis and management in multiple gestations.