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A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
Genitourinary infections and their association with preterm labor
Lorie F Cram1, Maria-isabel Zapata, Eugene C Toy
1Department of Family Practice, CHRISTUS St. Joseph Hospital, Houston, Texas 77002 USA.
American Family Physician
|February 1, 2002
Summary
Genitourinary infections, like asymptomatic bacteriuria, increase preterm delivery risk. Early diagnosis and treatment by family physicians can significantly reduce this risk, improving perinatal outcomes.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Family Medicine
Background:
- Preterm delivery is a leading cause of perinatal mortality in the US.
- Genitourinary infections can trigger uterine contractions via cytokines and prostaglandins.
- Several genitourinary infections are strongly linked to preterm birth.
Purpose of the Study:
- To review the association between genitourinary infections and preterm delivery.
- To emphasize the role of family physicians in managing these infections.
- To highlight strategies for reducing preterm delivery risk.
Main Methods:
- Literature review on genitourinary infections and preterm delivery.
- Analysis of the role of specific microorganisms (e.g., bacteria, Chlamydia trachomatis).
- Discussion of diagnostic and treatment approaches.
Main Results:
- Asymptomatic bacteriuria, gonococcal cervicitis, and bacterial vaginosis show a strong association with preterm delivery.
- The role of Chlamydia trachomatis, Trichomonas vaginalis, and Ureaplasma urealyticum requires further clarification.
- Microbial release of cytokines and prostaglandins can induce preterm labor.
Conclusions:
- Genitourinary infections are a significant risk factor for preterm delivery.
- Family physicians play a crucial role in diagnosing and treating these infections.
- A rational approach to genitourinary health can substantially decrease the incidence of preterm birth.
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