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Published on: August 4, 2023
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Corneal staining in hydrogel lens wearers.
Kelly K Nichols1, G Lynn Mitchell, Karen M Simon
1Ohio State University College of Optometry, Columbus, Ohio, USA. Nichols.214@osu.edu
Summary
Corneal staining is common in hydrogel contact lens wearers, particularly in the inferior cornea. Noncompliance with lens care and replacement schedules significantly increases the risk of moderate-to-severe staining.
Area of Science:
- Ophthalmology
- Optometry
- Biomaterials Science
Background:
- Corneal staining is a frequent complication associated with hydrogel contact lens wear.
- Understanding the contributing factors is crucial for improving lens safety and patient outcomes.
Purpose of the Study:
- To identify factors associated with corneal staining in hydrogel contact lens wearers.
- Investigated variables included lens type, wear duration, replacement schedule, care systems, and medication use.
Main Methods:
- Evaluated 500 successful full-time hydrogel contact lens wearers across 20 clinical sites.
- Corneal fluorescein staining was assessed in five regions and graded for severity (0-4).
Main Results:
- 55.7% of wearers exhibited some corneal staining; 8.0% had moderate-to-severe staining.
- Inferior cornea showed the most severe staining.
- Noncompliance with lens care systems, use of rewetting drops, and conventional lenses without a replacement schedule were linked to increased staining.
- Noncompliance with care systems, replacement schedules, and lens power were associated with moderate-to-severe staining.
Conclusions:
- Corneal staining is prevalent in hydrogel lens wearers and influenced by multiple factors.
- Moderate-to-severe staining is significantly associated with noncompliance in care system use, conventional replacement schedules, and lens power.

