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DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
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DNA hybridization arrays for gene expression analysis of human oral cancer

R Todd1, D T W Wong

  • 1Laboratory of Oral & Maxillofacial Surgery, Harvard School of Dental Medicine, Boston, MA 02115, USA. randy_todd@hms.harvard.edu

Journal of Dental Research
|February 7, 2002
PubMed

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DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...