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Updated: Apr 20, 2026

Multiplexed Fluorescent Microarray for Human Salivary Protein Analysis Using Polymer Microspheres and Fiber-optic Bundles
Published on: October 10, 2013
Emerging horizons of salivary diagnostics for periodontal disease
L Fuentes1, M Yakob1, D T W Wong1
1Centre for Oral/Head &Neck Oncology Research, University of California, Los Angeles, 73017 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
Abstract:
The field of salivary diagnostics to allow risk determination for periodontal diseases is advancing. New technologies in proteomics, genomics and nanotechnologies have continued the discovery of discriminatory periodontal disease biomarkers. This review briefly overviews biomarker studies that have been completed in saliva for the detection of periodontal disease since 2010. Disease specific biomarkers could be used in risk determination, treatment planning and disease progression. Currently, diagnostic tests are commercially available, and the development of point-of-care tests is expanding. Even though challenges remain, salivary diagnostics for periodontal disease is promising and could facilitate the diagnostics and treatment in a clinical practice by dental practitioners.
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