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An eruption secondary to intravenous immunoglobulin therapy
Diya F Mutasim1, Pranav B Sheth
1Department of Dermatology, University of Cincinnati, OH 45267-0592, USA. diya.mutasim@uc.edu
Cutis
|February 7, 2002
Abstract:
A 42-year-old woman presented with a recurrent eruption over the distal extremities. Lesions formed a few days after initiation of intravenous immunoglobulin (IVIg) therapy and lasted 2 to 3 weeks after therapy completion. Results of a histologic examination revealed parakeratosis, exocytosis, and spongiosis. The clinical and histologic findings are similar to previous reports. The mechanism of this eruption is not known.