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Periungual myxoid neurofibroma
Robyn F Gmyrek1, Robert Beer, David N Silvers
1Department of Dermatology, Columbia Presbyterian Medical Center, New York, New York, USA.
Cutis
|February 7, 2002
Summary
A rare myxoid neurofibroma, a type of nerve sheath tumor, was found on a woman's finger. This case highlights the unusual presentation and location of this benign tumor.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Neurofibromas are benign tumors arising from nerve sheath cells.
- Myxoid neurofibromas represent a specific histological subtype, often characterized by a myxoid matrix.
- Tumors of the hand and digits, particularly those in the periungual region, can present diagnostic challenges.
Observation:
- A 34-year-old female patient presented with a slow-growing, asymptomatic nodule on her left index finger.
- The nodule had been present for approximately two years prior to presentation.
- The lesion was located in the periungual area, making it clinically noticeable.
Findings:
- Surgical excision of the nodule was performed.
- Histopathological examination confirmed the diagnosis of a myxoid neurofibroma.
- The tumor exhibited characteristic myxoid stromal changes and proliferation of nerve sheath cells.
Implications:
- This case underscores the importance of considering rare soft tissue tumors in the differential diagnosis of finger nodules.
- The periungual location is an uncommon site for neurofibromas, necessitating awareness among clinicians.
- Reporting such rare occurrences contributes valuable data for understanding the spectrum and behavior of neurofibromas.