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Updated: Aug 12, 2026
08:22
In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
[Reversible myocardial ischemia in hypothyroidism: Case report]
I Quevedo1, L Mosso, J M Domínguez
1Departamentos de Endocrinología, Enfermedades Cardiovasculares, Medicina Nuclear, Facultad de Medicina, Pontificia Universidad Católica de Chile.
Revista Medica De Chile
|February 12, 2002
Summary
Hypothyroidism can cause silent myocardial ischemia, a reversible heart condition. Thyroid hormone replacement therapy effectively restored normal heart function and exercise capacity in a hypothyroid patient.
Area of Science:
- Cardiology
- Endocrinology
Background:
- Hypothyroidism is associated with cardiovascular complications.
- Silent myocardial ischemia in hypothyroid patients is a recognized but less common presentation.
Observation:
- A 49-year-old male presented with an abnormal exercise electrocardiogram.
- He had laboratory-confirmed hypothyroidism, asthenia, and voice changes.
- Thallium myocardial perfusion imaging revealed exercise-induced coronary flow alterations in the left ventricle.
Findings:
- Thyroid hormone substitution therapy was initiated.
- Coronary angiography performed three months post-treatment was normal.
- A six-month follow-up showed normal Thallium perfusion and exercise electrocardiogram results.
Implications:
- This case highlights the importance of considering thyroid dysfunction in patients with unexplained ischemic changes.
- Thyroid hormone replacement can reverse myocardial ischemia in hypothyroid individuals.
- Early detection and treatment of hypothyroidism can prevent potentially serious cardiac events.
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