Related Experiment Videos
CD45 exon 4 point mutation does not confer susceptibility to type 1 diabetes mellitus or Graves' disease
1Medical Department 1, Division of Endocrinology, Centre of Internal Medicine, Johann Wolfgang Goethe University Hospital, Theodor-Stern-Kai 7, D-60590 Frankfurt/Main, Germany.
Abstract:
A point mutation in the leukocyte common antigen (CD45, C-->G77, exon 4) was investigated in patients with type 1 diabetes (IDDM), patients with Graves' disease and controls. The distribution did not differ significantly between patients and controls. This CD45 variant does not therefore confer susceptibility to either IDDM or Graves' disease.