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Molecular analysis of HLA-DRB1 polymorphism in north-east Spain

S Vidal¹, M P Morante, E Moga

¹Department of Immunology, Hospital Sant Pau and Institute Rec. Sant Pau, Pare Claret 167, Barcelona 08025, Spain. Svidal@hsp.santpau.es

European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics

|February 14, 2002

Abstract:

The DRB1* polymorphism in 941 randomly selected individuals from the Umbilical Cord Blood Bank of Barcelona (92.75% of Spanish origin) was determined by sequence-based typing. The HLA profile was similar to that of other Mediterranean populations, with DRB1*0701 and *0301 being the most frequent alleles. This may be a consequence of the mixture of alleles as a result of migration from contiguous geographical areas.

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