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Updated: Aug 11, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
Published on: March 12, 2016
[Reversed trabeculectomy for treatment of glaucoma]
1Department of Ophthalmology, The Central Hospital, Shaoyang, Hunan 422000, China.
Objective:
To reduce the postoperative blocking of the filtration canal in routine trabeculectomy with modification.
Methods:
The modification of the procedure of routine trabeculectomy was that one end of the 4.0 mm x 1.5 mm deep layer scleral tissue including part of trabecular meshwork was not cut. Instead, the free end of the strip of deep scleral tissue was vertically rotated and sutured on the deep layer of the scleral bed posterior to it. The projection of the strip was utilized to prevent postoperative blocking of filtration canal.
Results:
The mean period of postoperative follow-up was 23.5 months (range, 12 -- 36 months). In the treatment group (38 eyes of 33 cases), the intraocular pressure (IOP) was lowered from preoperative (25.41 plus minus 2.41) mm Hg to postoperative (14.74 plus minus 0.90) mm Hg. The IOP was lowered from preoperative (24.96 plus minus 1.35) mm Hg to postoperative (19.40 plus minus 1.43) mm Hg in the control group (40 eyes of 33 cases). The success rates were 94.7% and 77.5% in the treatment and control group respectively.
Conclusions:
The modified trabeculectomy is safe, easy to perform, and can effectively relieve the postoperative blocking of the filtration canal, control postoperative IOP and reduce postoperative recurrence.
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