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[Viral-bacterial-fungal associations in chronic tonsillitis in children]
I A Gudima1, L I Vasil'eva, L E Bragina
1State Medical University, Research Institute for Plaque Control, Rostov-on-Don, Russia.
Abstract:
The microflora of palatal tonsils was studied in 84 children with chronic tonsillitis in comparison with that in the control group of 38 healthy children. In most of the sick children viral-bacterial and less frequently viral-bacterial-fungal associations were detected with the prevalence of reo- and adenoviruses, Epstein-Barr viruses, coagulase negative staphylococci and Staphylococcus aureus, as well as peptostreptococci. Adhesive activity and persistence factors among the main bacterial pathogens were shown to be widely prevalent. The depth of the lesion of tonsillar tissue by the infective agents of bacterial and fungal nature, as well as their persistence potential, depended on the taxonomic position of these microorganisms.
Insights
Chronic tonsillitis in children involves complex viral-bacterial and fungal infections in palatal tonsils. Key pathogens like adenoviruses and Staphylococcus aureus exhibit significant adhesive and persistence factors, influencing infection depth.
Area of Science:
- Microbiology
- Pediatrics
- Infectious Diseases
Background:
- Chronic tonsillitis is a common pediatric condition.
- The palatal tonsil microflora in chronic tonsillitis requires further investigation.
- Understanding microbial associations is crucial for effective treatment.
Purpose of the Study:
- To analyze the microflora composition of palatal tonsils in children with chronic tonsillitis.
- To compare the tonsillar microflora of sick children with that of healthy controls.
- To identify prevalent pathogens and their characteristics in chronic tonsillitis.
Main Methods:
- Microbiological analysis of palatal tonsil samples from 84 children with chronic tonsillitis.
- Comparison with samples from 38 healthy children (control group).
- Identification of viral, bacterial, and fungal agents, and assessment of bacterial adhesive and persistence factors.
Main Results:
- Viral-bacterial and viral-bacterial-fungal associations were common in children with chronic tonsillitis.
- Prevalent pathogens included reoviruses, adenoviruses, Epstein-Barr virus, coagulase-negative staphylococci, Staphylococcus aureus, and peptostreptococci.
- High prevalence of adhesive activity and persistence factors was observed in main bacterial pathogens.
Conclusions:
- The microflora in chronic tonsillitis is characterized by complex polymicrobial associations.
- Specific viruses and bacteria, particularly Staphylococcus aureus, play a significant role.
- Microbial characteristics like adhesive activity and persistence potential influence the severity and depth of tonsillar tissue lesions.