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Updated: Oct 1, 2026

05:17
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Turn formation initiated by a bissulfoximine motif: synthesis and structural investigation
Carsten Bolm1, Dirk Müller, Christian P R Hackenberger
1Institut für Organische Chemie der RWTH Aachen, Professor-Pirlet-Str.1, D-52056 Aachen, Germany. carsten.bolm@oc.rwth-aachen.de
Organic Letters
|March 15, 2002
Abstract:
[reaction: see text] Bissulfoximines containing heterochiral SulfCO-SulfCO units may be used as molecular templates, which induce U-shaped conformations in peptidelike structures. The synthesis of such molecules has been investigated, and the structural requirements of this new turn motif have been identified.

