Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

ARDS. The future.

Hector R Wong1

  • 1Division of Critical Care Medicine, Children's Hospital Medical Center, Children's Hospital Research Foundation, Cincinnati, Ohio, USA.

Critical Care Clinics
|March 26, 2002
PubMed
Summary
This summary is machine-generated.

Genomic insights into Acute Respiratory Distress Syndrome (ARDS) can improve patient outcomes by revealing individual immune responses. Understanding these immunophenotypes allows for targeted therapies against ARDS.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Machine learning-driven identification of the gene-expression signature associated with a persistent multiple organ dysfunction trajectory in critical illness.

EBioMedicine·2023
Same author

Biomarker-based risk model to predict persistent multiple organ dysfunctions after congenital heart surgery: a prospective observational cohort study.

Critical care (London, England)·2023
Same author

Identification of a pediatric acute hypoxemic respiratory failure signature in peripheral blood leukocytes at 24 hours post-ICU admission with machine learning.

Frontiers in pediatrics·2023
Same author

Biomarker-based risk model to predict persistent multiple organ dysfunctions after congenital heart surgery â€" A prospective observational cohort study.

Research square·2023
Same author

Biomarkers estimating baseline mortality risk for neonatal sepsis: nPERSEVERE: neonate-specific sepsis biomarker risk model.

Pediatric research·2022
Same author

Electrolyte derangements in critically ill children receiving balanced versus unbalanced crystalloid fluid resuscitation.

BMC nephrology·2022
Same journal

Critical Care and Contagion: Evolving Frontiers of Infectious Diseases in the Modern Intensive Care Unit.

Critical care clinics·2026
Same journal

Advances and Challenges in Sepsis Care in Low-Resource Settings.

Critical care clinics·2026
Same journal

The Respiratory Triple Pandemic in the Intensive Care Unit: Epidemiology, Clinical Features and Management of COVID-19, Influenza and Respiratory Syncytial Virus.

Critical care clinics·2026
Same journal

Antibiotic Stewardship for the Intensivist.

Critical care clinics·2026
Same journal

Infection Prevention and Control in the Intensive Care Unit.

Critical care clinics·2026
Same journal

Antibiotic Considerations in the Critically Ill: Empiric Choices and Dosing.

Critical care clinics·2026
See all related articles

Area of Science:

  • Pulmonary Medicine
  • Immunology
  • Genomics

Background:

  • Acute Respiratory Distress Syndrome (ARDS) poses significant clinical challenges.
  • Understanding ARDS heterogeneity and individual patient responses is crucial for improving outcomes.
  • Current therapeutic strategies for ARDS require refinement.

Purpose of the Study:

  • To explore the potential of genomics in understanding ARDS pathophysiology.
  • To highlight the importance of characterizing individual immunophenotypes in ARDS patients.
  • To identify novel molecular and genetic targets for ARDS treatment.

Main Methods:

  • Utilizing genomic technologies to analyze patient data.
  • Characterizing the immunophenotypes of individual ARDS patients.

Related Experiment Videos

  • Investigating endogenous cytoprotective mechanisms like heat shock response and HO-1.

    • Main Results:

    • Genomics offers a powerful approach to unraveling ARDS heterogeneity.
    • Individual immunophenotypes can guide more rational therapeutic interventions.
    • Understanding molecular and genetic factors may lead to new treatment avenues.

    Conclusions:

    • Personalized medicine approaches, driven by genomics, are essential for advancing ARDS care.
    • Targeting specific immune pathways and cytoprotective mechanisms holds promise for future ARDS therapies.
    • Further research into the genetic basis of ARDS is warranted to improve patient outcomes.