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Cytotoxic diterpenoids from Euphorbia pekinensis
Ling-Yi Kong1, Yi Li, Xian-Li Wu
1Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, PR China. lykong@jlonline.com
Planta Medica
|March 27, 2002
Abstract:
A new diterpenoid, named euphpekinensin, along with three known diterpenoids, was isolated from the roots of Euphorbia pekinensis for the first time and the structures were elucidated by spectral analysis. The 2D-NMR techniques such as 1H-1H COSY, HMQC, HMBC and NOESY spectra were mainly applied to determine the structure of the new diterpenoid. The four diterpenoids showed cytotoxic activity against human KB cells in vitro.