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[Brain monoamine oxidase in prematurely aging OXYS rats]
1Institute of Cytology and Genetics, Siberian Branch, Russian Acad. Sci., Lavrenteva 10 av., 630090, Novosibirsk, Russia.
Voprosy Meditsinskoi Khimii
|April 3, 2002
Abstract:
Rats OXYS with manifestations of genetically determined premature aging and OXYR free from these manifestation were studied. Eight month old OXYS and OXYR rats were characterized by similar brain stem MAO A and MAO B activities and their control at the transcription level. In hemispheres of 8 month old OXYS rats MAO A activity was higher than in OXYR. Emotional stress did not affect either MAO A or MAO B in brain stem of the two strains, and lowered MAO A activity in hemispheres of OXYS rats.