Related Experiment Videos
Brine shrimp lethality assay of Bacopa monnieri
Prashanth D'Souza1, Mundkinajeddu Deepak, Padmaja Rani
1Bioassay Unit, M/s Natural Remedies Pvt Ltd, 5B Veerasandra Indl Area, Hosur Road, Bangalore 561 229, India.
Phytotherapy Research : PTR
|April 5, 2002
Abstract:
Successive petroleum ether, chloroform, ethanol and water extracts, a saponin rich fraction (SRF) and bacoside A isolated from Bacopa monnieri were tested for brine shrimp lethality. Successive ethanol extracts and SRF showed potent activity. Bacoside A showed the maximum activity with a LC(50) of 38.3 microg/mL. The results confirmed the previous reports of an anticancer effect of Bacopa monnieri and suggest bacoside A as the active constituent.