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Deep cerebral venous thrombosis in adults
Shuhong Ming1, Zengfei Qi, Luning Wang
1Respiratory Department, Beijing Hospital, Beijing 100730, China. yytan77@hotmail.com
Chinese Medical Journal
|April 10, 2002
Summary
Non-acute intracranial deep venous thrombosis can be safely and effectively treated with thrombolysis and anticoagulation. Digital subtraction angiography (DSA) offers superior diagnostic accuracy compared to MRI for this condition.
Area of Science:
- Neurology
- Vascular Medicine
- Radiology
Background:
- Non-acute intracranial deep venous thrombosis presents diagnostic and therapeutic challenges.
- Understanding its pathogenesis, clinical course, and imaging characteristics is crucial.
Purpose of the Study:
- To investigate the pathogenesis, clinical features, radiographic findings, and therapeutic outcomes of non-acute intracranial deep venous thrombosis in adults.
Main Methods:
- Retrospective review of five adult patients diagnosed with non-acute intracranial deep venous thrombosis.
- Diagnostic workup included computed tomography, magnetic resonance imaging, and angiography.
- Treatment involved thrombolytic and systemic anticoagulant therapy.
Main Results:
- The study included three men and two women aged 22-49 years with symptom duration of 1-7 months.
- Four patients had associated venous sinus thrombosis; three had no evident predisposing factors.
- Neurological symptoms and signs improved following thrombolytic and anticoagulant therapy.
Conclusions:
- Digital subtraction angiography (DSA) demonstrates higher sensitivity and accuracy than MRI for diagnosing intracranial deep venous thrombosis.
- DSA is valuable for assessing treatment efficacy.
- Thrombolysis and anticoagulation are safe and effective for non-acute intracranial deep venous thrombosis, extending beyond the acute stage.