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Fiber-optic biosensors--an overview.
Dolores Marazuela1, María Cruz Moreno-Bondi
1Optical Sensors Group, Department of Analytical Chemistry, Faculty of Chemistry, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Analytical and Bioanalytical Chemistry
|April 10, 2002
Summary
Optical fiber biosensors offer real-time, low-cost analysis for industrial, environmental, and clinical needs. Recent advancements focus on miniaturization and multianalyte detection for improved biosensing applications.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
- Optoelectronics
Background:
- Modern laboratory analysis faces cost and time constraints.
- Growing demand for real-time, low-cost monitoring in various sectors.
- Need for advanced biosensing technologies in industrial, environmental, clinical, and food processing applications.
Purpose of the Study:
- To review progress in optical fiber biosensors over the past five years.
- To discuss key aspects of sensor development, including miniaturization, integrated systems, and multianalyte determination.
- To highlight future research directions in optical fiber biosensor technology.
Main Methods:
- Review of recent scientific literature on optical fiber biosensors.
- Classification of biosensors based on biorecognition elements (enzymes, whole cells, antibodies, nucleic acids, biomimetic polymers).
- Analysis of analytical characteristics and applications of various fiber-optic biosensor types.
Main Results:
- Significant advancements in optical fiber biosensor technology over the last five years.
- Emerging trends in miniaturization, integrated systems, and multianalyte detection.
- Diverse applications demonstrated across industrial, environmental, clinical, and food monitoring.
Conclusions:
- Optical fiber biosensors are a promising technology for real-time, cost-effective analysis.
- Continued research is expected to enhance sensor capabilities and expand their application scope.
- The development of novel biorecognition elements will drive future innovation in the field.