Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Contamination problem with sentinel node localization procedure: a case study.

John Warner1, Steven Hovey, Elpida S Crawford

  • 1Roswell Park Cancer Institute and State University of New York at Buffalo, Buffalo, New York, USA. jwarner@roswellpark.org

Journal of Nuclear Medicine Technology
|April 12, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From genes to trajectories: mapping genetic influences on Huntington's disease progression.

Bioinformatics (Oxford, England)·2026
Same author

FIP200 regulates plasma B cell differentiation via mitochondrial and heme homeostasis.

The Journal of experimental medicine·2025
Same author

Affinity gaps among B cells in germinal centers drive the selection of MPER precursors.

Nature immunology·2024
Same author

Antibody production relies on the tRNA inosine wobble modification to meet biased codon demand.

Science (New York, N.Y.)·2024
Same author

Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice.

Immunity·2022
Same author

Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.

Immunity·2021
Same journal

<sup>18</sup>F-NaF PET/CT Versus <sup>18</sup>F-FDG PET/CT for Baseline Mapping in Ollier Disease: A Pediatric Case.

Journal of nuclear medicine technology·2026
Same journal

Incidental Detection of Aggressive HER2-Positive Breast Cancer on <sup>99m</sup>Tc-Sestamibi Parathyroid Scintigraphy.

Journal of nuclear medicine technology·2026
Same journal

Structured Educational Tours in Hospital-Based Radiopharmaceutical Production: Balancing Safety and Learning.

Journal of nuclear medicine technology·2026
Same journal

Development of a Phantom for Evaluating Image Quality and Partial-Volume Effects in Hot and Cold Regions in Small-Animal SPECT and PET.

Journal of nuclear medicine technology·2026
Same journal

Nonuniformity in a Certified <sup>68</sup>Ge PET Cylinder Phantom: Implications for Normalization Quality Assurance.

Journal of nuclear medicine technology·2026
Same journal

Reducing Formation of Suspected Tracer Microemboli During Preparation of <sup>99m</sup>Tc-Tagged Heat-Damaged Red Blood Cells.

Journal of nuclear medicine technology·2026
See all related articles

Sentinel node (SN) localization using lymphoscintigraphy can be complicated by skin contamination from radiopharmaceuticals. Careful procedural observation prevented misinterpretation of the SN location in this melanoma case.

Area of Science:

  • Nuclear medicine imaging
  • Dermatologic oncology
  • Surgical oncology

Background:

  • Sentinel node biopsy is crucial for melanoma staging.
  • Lymphoscintigraphy is a standard technique for sentinel node localization.
  • Potential complications include radiopharmaceutical skin contamination.

Observation:

  • A 60-year-old male patient with back melanoma underwent lymphoscintigraphy.
  • Accidental skin contamination with the radiopharmaceutical occurred during dose administration.
  • Contamination posed a risk of misidentifying the sentinel node location.

Findings:

  • Despite skin contamination, careful monitoring of the lymphoscintigraphy procedure was performed.
  • The potential misinterpretation of the sentinel node's true location was successfully avoided.

Related Experiment Videos

  • Accurate sentinel node identification was maintained throughout the procedure.
  • Implications:

    • Highlights the importance of meticulous technique in lymphoscintigraphy.
    • Emphasizes vigilance to mitigate risks associated with radiopharmaceutical handling.
    • Ensures accurate staging and appropriate treatment planning for melanoma patients.