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Disinfectants that do.

Hugo Sax1, Didier Pittet

  • 1Infection Control Program, Department of Internal Medicine, University of Geneva Hospitals, Geneva, Switzerland.

Current Opinion in Infectious Diseases
|April 20, 2002
PubMed
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Biocides help control pathogens in healthcare, but this review explores their advances and potential to induce antimicrobial resistance. We examine hand hygiene, sterilization, and contamination challenges, including prion disease.

Area of Science:

  • Infection control and antimicrobial resistance
  • Healthcare-associated infections
  • Public health microbiology

Background:

  • Biocides are crucial for pathogen reduction in healthcare settings.
  • Effective use spans skin antisepsis, device sterilization, and environmental decontamination.
  • Emerging concerns include biocide resistance and its implications.

Purpose of the Study:

  • To review recent advancements in biocide applications for infection control.
  • To discuss challenges related to environmental contamination and prion diseases.
  • To critically evaluate the potential for biocides to induce antimicrobial resistance.

Main Methods:

  • Literature review of recent research on biocides in healthcare.
  • Analysis of data on hand hygiene, instrument sterilization, and decolonization.

Related Experiment Videos

  • Examination of studies investigating environmental contamination and prion disease transmission.

    • Main Results:

    • Advances in hand hygiene protocols and sterilization techniques are highlighted.
    • Mupirocin's role in decolonization strategies is discussed.
    • The potential for biocides to select for or induce resistance in pathogens remains a significant concern.

    Conclusions:

    • Biocides remain essential tools in healthcare infection prevention.
    • Ongoing research is needed to understand and mitigate biocide resistance.
    • Integrated strategies are necessary to address environmental contamination and emerging threats like prion diseases.