Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sequential antibiotic therapy.

Gavin D. Barlow1, Dilip Nathwani

  • 1Infection & Immunodeficiency Unit, Kings Cross Hospital, Tayside University Teaching Hospitals, Dundee, UK.

Current Opinion in Infectious Diseases
|April 20, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Introducing the global antimicrobial stewardship partnership hub (GASPH): creating conditions for successful global partnership collaboration.

JAC-antimicrobial resistance·2022
Same author

Public health and social measures to mitigate the health and economic impact of the COVID-19 pandemic in Turkey, Egypt, Ukraine, Kazakhstan, and Poland during 2020-2021: situational analysis.

BMC public health·2022
Same author

Cost-minimisation analysis of oritavancin for the treatment of acute bacterial skin and skin structure infections from a United Kingdom perspective.

The European journal of health economics : HEPAC : health economics in prevention and care·2022
Same author

BSAC Vanguard Series: The future of healthcare workers and antimicrobial stewardship-educate, innovate, or pay the price.

The Journal of antimicrobial chemotherapy·2022
Same author

Comparative efficacy of delafloxacin for complicated and acute bacterial skin and skin structure infections: results from a network meta-analysis.

BMC infectious diseases·2021
Same author

Current Antimicrobial Stewardship Practice and Education in Russian Hospitals: Results of a Multicenter Survey.

Antibiotics (Basel, Switzerland)·2021
Same journal

Use of gloves: current evidence vs. current use.

Current opinion in infectious diseases·2026
Same journal

Understanding challenges to prevention of healthcare related infections.

Current opinion in infectious diseases·2026
Same journal

Harnessing next-generation microbial diagnostics to optimize infection management in immunocompromised hosts.

Current opinion in infectious diseases·2026
Same journal

Epidemiology, treatment and outcomes of antimicrobial-resistant infections in hematopoietic stem cell transplant recipients.

Current opinion in infectious diseases·2026
Same journal

Dengue and chikungunya vaccines past, present and future: implications for travelers.

Current opinion in infectious diseases·2026
Same journal

Oropouche virus: viral evolution, epidemiological trends, and challenges for control.

Current opinion in infectious diseases·2026
See all related articles

Sequential antibiotic therapy offers a safe and cost-effective approach to treating severe bacterial infections by enabling an early switch to oral medication. This strategy improves healthcare quality and reduces hospital expenditure on antimicrobials.

Area of Science:

  • Infectious Diseases
  • Hospital Pharmacy
  • Health Economics

Background:

  • Antimicrobial drugs represent a significant hospital expenditure.
  • Traditional treatment for severe bacterial infections involves prolonged intravenous antibiotic therapy.
  • This conventional approach leads to unnecessary intravenous treatment durations and associated drawbacks.

Purpose of the Study:

  • To evaluate the benefits of sequential antibiotic therapy.
  • To highlight the importance of early oral switch in managing bacterial infections.
  • To emphasize the role of guidelines and multidisciplinary teams in optimizing sequential therapy.

Main Methods:

  • Review of current practices in antimicrobial therapy.
  • Analysis of the safety and efficacy of sequential antibiotic therapy.

Related Experiment Videos

  • Assessment of the impact on healthcare quality and cost-effectiveness.

    • Main Results:

    • Sequential antibiotic therapy ensures an early switch to oral medication in clinically stable patients.
    • This strategy is safe and leads to improved quality and cost-effectiveness in healthcare.
    • Implementation requires clear guidelines and multidisciplinary team support.

    Conclusions:

    • Sequential antibiotic therapy is a safe and effective strategy for managing severe bacterial infections.
    • Optimizing the timing of oral switch and exploring oral treatment for complex infections like osteomyelitis and endocarditis are future research priorities.
    • Evidence-based infection management will be enhanced by incorporating sequential antimicrobial therapy.