Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Post-infective diarrhoea.

J A Walker-Smith1

  • 1University of London, The Wellcome Trust Centre for the History of Medicine, London, UK. johnwalker_smith@hotmail.com

Current Opinion in Infectious Diseases
|April 20, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

With commentary.

Archives of disease in childhood·2010
Same author

12 articles of 1926.

Archives of disease in childhood·2010
Same author

Intractable diarrhea of infancy.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association·2009
Same author

Systemic vasculitis: a cause of indeterminate intestinal inflammation.

Journal of pediatric gastroenterology and nutrition·2006
Same author

Acetylated sialic acid residues and blood group antigens localise within the epithelium in microvillous atrophy indicating internal accumulation of the glycocalyx.

Gut·2004
Same author

Diagnostic role of upper gastrointestinal endoscopy in pediatric inflammatory bowel disease.

Journal of pediatric gastroenterology and nutrition·2004
Same journal

Use of gloves: current evidence vs. current use.

Current opinion in infectious diseases·2026
Same journal

Understanding challenges to prevention of healthcare related infections.

Current opinion in infectious diseases·2026
Same journal

Harnessing next-generation microbial diagnostics to optimize infection management in immunocompromised hosts.

Current opinion in infectious diseases·2026
Same journal

Epidemiology, treatment and outcomes of antimicrobial-resistant infections in hematopoietic stem cell transplant recipients.

Current opinion in infectious diseases·2026
Same journal

Dengue and chikungunya vaccines past, present and future: implications for travelers.

Current opinion in infectious diseases·2026
Same journal

Oropouche virus: viral evolution, epidemiological trends, and challenges for control.

Current opinion in infectious diseases·2026
See all related articles

Persistent diarrhea in developing countries, often caused by infections like Cryptosporidium and E. coli, requires complex management. Zinc supplementation shows promise in reducing its duration and aiding mucosal recovery.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health Nutrition

Background:

  • Persistent diarrhea, defined as diarrhea lasting over two weeks in developing countries, contributes significantly to child mortality.
  • While acute diarrhea mortality has decreased, persistent diarrhea remains a challenge.
  • Factors influencing the progression from acute to persistent diarrhea in developing communities are critical to understand.

Purpose of the Study:

  • To review the determinants of persistent diarrhea in developing countries.
  • To explore the role of specific enteropathogens in persistent diarrhea.
  • To evaluate the potential of zinc supplementation in managing persistent diarrhea and promoting mucosal healing.

Main Methods:

  • Literature review of studies on persistent diarrhea in developing countries.

Related Experiment Videos

  • Analysis of etiological factors, including infectious agents like Cryptosporidium parvum and enteropathogenic Escherichia coli.
  • Examination of the role of small intestinal mucosal damage and the impact of zinc supplementation.

    • Main Results:

    • Cryptosporidium parvum infection was a significant factor in persistent diarrhea in West Africa.
    • Enteropathogenic Escherichia coli was identified in 50% of infants with persistent diarrhea in Brazil and India.
    • Zinc supplementation demonstrates potential in reducing the duration of persistent diarrhea and aiding small intestinal mucosal recovery.

    Conclusions:

    • Persistent diarrhea is a complex condition in developing countries with significant morbidity.
    • Infectious agents and sustained mucosal damage are key factors.
    • Zinc supplementation offers a promising therapeutic strategy for persistent diarrhea, though broader public health supplementation remains debated.