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[Tumor markers in breast neoplasm].
Silvia Coronato1, Graciela E Laguens, Osvaldo M Spinelli
1Cátedra de Patología B, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina. scorona@atlas.med.unlp.edu.ar
Medicina
|April 23, 2002
Summary
Breast cancer remains a leading diagnosis for women. New molecular markers offer hope for reducing mortality by improving risk identification, prognosis prediction, and therapy response assessment.
Area of Science:
- Oncology
- Molecular Biology
- Biochemistry
Context:
- Breast cancer is the most common cancer diagnosis in women globally.
- Despite advancements, breast cancer mortality rates have remained stagnant for two decades.
- Molecular biology has enhanced understanding of breast cancer's fundamental mechanisms.
Purpose:
- To review traditional and novel molecular markers for breast cancer.
- To assess the clinical utility and routine relevance of these markers.
- To highlight markers aiding in risk stratification and treatment personalization.
Summary:
- This article examines established and emerging molecular markers in breast cancer management.
- It discusses their role in identifying at-risk individuals and predicting disease outcomes.
- The evaluation of marker utility in clinical practice is a key focus.
Impact:
- Potential to reduce breast cancer mortality through improved diagnostics and targeted therapies.
- Facilitates personalized medicine approaches in breast cancer care.
- Informs clinical decision-making for patient risk assessment and treatment selection.