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[Complication associated with celiac disease].

R Baños Madrid¹, J Mercader Martínez, F Sánchez Bueno

¹Servicio de Medicina del Aparato Digestivo, Hospital Universitario Virgen de la Arrixaca, Murcia.

Anales De Medicina Interna (Madrid, Spain : 1984)

|May 7, 2002

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Enteropathy associated T-cell lymphoma (EATL) is a severe complication of celiac sprue. This case highlights a jejunal EATL diagnosis 15 years after initial celiac disease diagnosis, emphasizing the need for vigilance.

Area of Science:

Gastroenterology
Oncology
Immunology

Background:

Celiac disease (CD) patients have a 2-fold increased risk of malignancy.
Small intestinal lymphomas, predominantly T-cell lymphomas, account for 50% of CD-associated malignancies.
Enteropathy associated T-cell lymphoma (EATL) is the most serious complication of celiac sprue.

Observation:

A 33-year-old woman was diagnosed with celiac sprue and improved on a gluten-free diet.
Fifteen years later, she presented with fever and abdominal pain.
Laparotomy revealed a perforated jejunal tumor.

Findings:

The patient was diagnosed with celiac disease-associated T-cell lymphoma of the jejunum.
This case illustrates a rare but serious long-term complication of celiac disease.

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Implications:

Highlights the importance of long-term surveillance for gastrointestinal malignancies in celiac disease patients.
Underscores the need for awareness among clinicians regarding EATL as a potential complication.
Suggests further research into the pathogenesis and early detection of EATL in celiac patients.